2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-120809
    Spiramycin III
    		Inhibitor
    Spiramycin III (SPMIII) is a main component of Spiramycin. Spiramycin (HY-100593) is a macrolide antibiotic produced by Streptomyces ambofaciens with against bacteria and Toxoplasma gondii activities, and also has antiparasitic effect.
    Spiramycin III
  • HY-N5109
    Cheilanthifoline
    		Inhibitor 99.95%
    Cheilanthifoline, an alkaloid, is isolated from Corydalis calliantha. Cheilanthifoline exhibits antiplasmodial activities against Plasmodium falciparum, with IC50s of 0.90 μg/mL and 1.22 μg/mL for wild type (TM4) and multidrug resistant (K1) strains, respectively.
    Cheilanthifoline
  • HY-N12077
    Eurycomanol 2-O-β-D-glucopyranoside
    		Inhibitor 99.79%
    Eurycomanol 2-O-β-D-glucopyranoside (compound 4) is a natural product that can be obtained from Eurycoma longifolia. Eurycomanol 2-O-β-D-glucopyranoside has the potential for anti-malarial research.
    Eurycomanol 2-O-β-D-glucopyranoside
  • HY-119459R
    Fluopyram (Standard)
    		Inhibitor
    Fluopyram (Standard) is the analytical standard of Fluopyram (HY-119459). This product is intended for research and analytical applications. Fluopyram is an orally active succinate dehydrogenase inhibitor, antifungal and nematicide. Fluopyram inhibits succinate dehydrogenase activity, activates CAR/PXR nuclear receptors, and increases caspase-3, TNF-α and NF-κB. Fluopyram inhibits the growth of F. virguliforme, Botrytis cinerea and Alternaria solani with EC50 values of 3.35, 5.389 and 0.244 µg/mL, respectively. Fluopyram induces liver and thyroid tumor formation. Fluopyram is nephrotoxic and embryotoxic.
    Fluopyram (Standard)
  • HY-17035R
    Doramectin (Standard)
    		Inhibitor
    Doramectin (Standard) is the analytical standard of Doramectin. This product is intended for research and analytical applications. Doramectin is a derivative of Ivermectin (HY-15310). Doramectin is a potent antiparasitic antibiotic. Doramectin is an active compound against S.mansoni in an NMRI mouse infection model.
    Doramectin (Standard)
  • HY-B1118R
    Secnidazole (Standard)
    		Inhibitor
    Secnidazole (Standard) is the analytical standard of Secnidazole. This product is intended for research and analytical applications. Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis.
    Secnidazole (Standard)
  • HY-101715
    Panidazole
    		Inhibitor 99.74%
    Panidazole is an amoebicide.
    Panidazole
  • HY-B0879AR
    Suramin sodium salt (Standard)
    		Inhibitor
    Suramin (sodium salt) (Standard) is the analytical standard of Suramin (sodium salt). This product is intended for research and analytical applications. Suramin sodium salt (Suramin hexasodium salt) is a reversible and competitive protein-tyrosine phosphatases (PTPases) inhibitor. Suramin sodium salt is a potent inhibitor of sirtuins: SirT1 (IC50=297 nM), SirT2 (IC50=1.15 μM), and SirT5 (IC50=22 μM). Suramin sodium salt is a competitive inhibitor of reverse transcriptase (DNA topoisomerase II: IC50=5 μM). Suramin sodium salt is a potent SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) inhibitor. Suramin sodium salt efficiently inhibits IP5K and is an antiparasitic, anti-neoplastic and anti-angiogenic agent.
    Suramin sodium salt (Standard)
  • HY-W357093
    2-Chloro-2-deoxy-D-glucose
    		Inhibitor
    2-Chloro-2-deoxy-D-glucose is a 2-substituted glucose analog. 2-Chloro-2-deoxy-D-glucose inhibits the in vitro growth of P. falciparum. 2-Chloro-2-deoxy-D-glucose against a CQR strain with an IC50 value of 8.5 nM at the glucose concentration 5 mM.
    2-Chloro-2-deoxy-D-glucose
  • HY-W588212
    trans-Permethrin
    		Inhibitor 99.88%
    trans-Permethrin is a transconfiguration of Permethrin (HY-B0887). Permethrin is an insecticide and neurotoxin.
    trans-Permethrin
  • HY-126425
    NCGC00262650
    		Inhibitor 99.22%
    NCGC00262650 is a potent apical membrane antigen 1-rhoptry neck protein 2 (AMA1-RON2) interaction inhibitor. NCGC00262650 can block entry of merozoites into red blood cells with an IC50 of 9.8 μM.
    NCGC00262650
  • HY-B0825R
    (E)-Fenpyroximate (Standard)
    		Inhibitor
    (E)-Fenpyroximate (Standard) is the analytical standard of (E)-Fenpyroximate. This product is intended for research and analytical applications. (E)-Fenpyroximate is a potent acaricide.
    (E)-Fenpyroximate (Standard)
  • HY-126057
    (R)-Praziquantel
    		Inhibitor 99.10%
    (R)-Praziquantel, the active enantiomer of Praziquantel, is a partial agonist of the human 5-HT2B receptor. (R)-Praziquantel acts as an antischistosomal eutomer.
    (R)-Praziquantel
  • HY-121002
    Alstonine
    		Inhibitor
    Alstonine is a major indole alkaloid compound of a plant-based remedy. Alstonine has antipsychotic, anxiolytic, anticancer and antimalarial properties.
    Alstonine
  • HY-D0143R
    Quinine (Standard)
    		Inhibitor
    Quinine (Standard) is the analytical standard of Quinine. This product is intended for research and analytical applications. Quinine is an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV with an IC50 of 169 μM.
    Quinine (Standard)
  • HY-B2031R
    Pyriproxyfen (Standard)
    		Inhibitor
    Pyriproxyfen (S-31183) (Standard) is the analytical standard of Pyriproxyfen. This product is intended for research and analytical applications. Pyriproxyfen is a juvenile hormone analog and insect growth regulator. Pyriproxyfen is used in research related to dengue fever and malaria.
    Pyriproxyfen (Standard)
  • HY-N7583
    Norcaesalpinin E
    		Inhibitor
    Norcaesalpinin E, a C-17-norcassane-type diterpene found in Caesalpinia crista, is a Plasmodium falciparum growth inhibitor with an IC50 of 90 nM. Norcaesalpinin E induces dose-dependent growth inhibition of Plasmodium falciparum. Norcaesalpinin E can be used for the research of malaria.
    Norcaesalpinin E
  • HY-B0887R
    Permethrin (Standard)
    		Inhibitor
    Permethrin (Standard) is the analytical standard of Permethrin. This product is intended for research and analytical applications. Permethrin (NRDC-143) is an insecticide, acaricide, and insect repellent; functions as a neurotoxin, affecting neuron membranes by prolonging sodium channel activation.
    Permethrin (Standard)
  • HY-B1111R
    Amitraz (Standard)
    		Inhibitor
    Amitraz (Standard) is the analytical standard of Amitraz. This product is intended for research and analytical applications. Amitraz is a non-systemic acaricide and insecticide with alpha-adrenergic agonist activity that interacts with octopamine receptors in the central nervous system and inhibits monoamine oxidase and prostaglandin synthesis.
    Amitraz (Standard)
  • HY-156895
    Ile-AMS
    		Inhibitor
    Ile-AMS is active active in P. falciparum, with an ABS IC50 of 1.19 nM.
    Ile-AMS
Parasite Isoform Comparison

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